Hypromellose Acetate Succinate USP NF Grade Manufacturers

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Hypromellose Acetate Succinate or Hydroxypropyl Methyl Cellulose Acetate Succinate or HPMC-AS USP NF Grade Manufacturers

Anmol Chemicals is a manufacturer supplier exporter of Hypromellose Acetate Succinate or Hydroxypropyl Methyl Cellulose Acetate Succinate or HPMC-AS and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.

We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.

Synonyms: Hydroxypropyl Methyl Cellulose Acetate succinate or Hypromellose Acetate Succinate or HPMC-AS
CAS Number: CAS Number: 71138-97-1, Molecular Weight: 286.28, Chemical Formula: C10H22O9, EINECS EC Number: 615-255-9, FEMA: ----,

Hydroxypropyl methylcellulose acetate succinate or hypromellose acetate succinate or HPMC-AS is an enteric coating material used for both regular enteric coating and sustained release formulations.

Specifications of Hypromellose Acetate Succinate USP NF Grade:
Hydroxypropyl methylcellulose acetate succinate;
Cellulose, 2-hydroxypropyl methyl ether, acetate hydrogen butanedioate;
Cellulose, 2-hydroxypropyl methyl ether, acetate succinate --- CAS 71138-97-1

DEFINITION
Hypromellose Acetate Succinate is a mixture of acetic acid and monosuccinic acid esters of hydroxypropyl methylcellulose. It contains NLT 12.0% and NMT 28.0% of methoxy groups (– OCH3 ), NLT 4.0% and NMT 23.0% of hydroxypropoxy groups (– OCH2CHOHCH3 ), NLT 2.0% and NMT 16.0% of acetyl groups (– COCH3 ), and NLT 4.0% and NMT 28.0% of succinoyl groups (– COC2H4COOH), calculated on the dried basis.

IDENTIFICATION
A. Infrared Absorption:
To pass the test.
Acceptance criteria: The IR spectrum of the Sample exhibits maxima only at the same wavelengths as a similarly obtained spectrum of USP Hypromellose Acetate Succinate.

ASSAY
Acetyl and Succinoyl Groups:
To pass the test by Chromatography
Acceptance criteria:
Acetyl groups (– COCH3 ): 2.0%–16.0% on the dried basis
Succinoyl groups (– COC2H4COOH): 4.0%–28.0% on the dried basis
Content of Methoxy and 2-Hydroxypropoxy Groups:
To pass the test by Chromatography
Acceptance criteria
Methoxy groups (– OCH3 ): 12.0%–28.0% on the dried basis
Hydroxypropoxy groups (– OCH2CHOHCH3 ): 4.0%–23.0% on the dried basis

Residue on Ignition:
Analysis: Determine at 600 ± 50C.
Acceptance criteria: NMT 0.20%
Limit of Free Acetic and Succinic Acids:
To pass the test.
Acceptance criteria: The sum of free acetic acid and free succinic acid is NMT 1.0%.
Loss on Drying:
Analysis: Dry at 105C for 1 h.
Acceptance criteria: NMT 5.0%
Viscosity—Capillary Methods:
To pass the test.
Acceptance criteria: 80%–120% of that stated on the label.

Keywords: Hydroxypropyl Methyl Cellulose Acetate Succinate, Hypromellose Acetate Succinate, HPMC-AS IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 71138-97-1 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.

ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIA

Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.

Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.

All products are Sold for Industrial Use only. No other use is permitted. Specifications provided are for reference. Grade approvals pending.

Hypromellose Acetate Succinate
Hydroxypropyl methyl cellulose acetate or HPMC-AS USP NF Grade Manufacturers