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for Active Substance to be imported into European Union (EU).Magnesium Sulfate USP Magnesium Sulphate BP Ph Eur IP Analytical Reagent FCC Food Grade Manufacturers, Magnesium Sulfate Heptahydrate Monohydrtse Dried & Anhydrous
CAS Number anhydrous 7487-88-9, monohydrate 14168-73-1, dried 15244-36-7, heptahydrate 10034-99-8,
Anmol Chemicals is a manufacturer supplier exporter of Magnesium Sulfate or Magnesium Sulphate Monohydrate Anhydrous Heptahydrate Dried and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
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Dried Magnesium Sulphate BP Ph Eur Grade Specifications Magnesium Sulfate
Dried Epsom Salts or Magnesium Sulphate Dried
Preparation
Magnesium Sulphate PasteDEFINITION
Dried Magnesium Sulphate contains not less than 62.0% and not more than 70.0% of MgSO4.
It may be prepared by drying magnesium sulphate at 100° until it has lost approximately 25% of its weight.CHARACTERISTICS
A white powder.
Freely soluble in water; dissolves more rapidly in hot water.IDENTIFICATION
Yields the reactions characteristic of magnesium salts and of sulphates.TESTS
Acidity or alkalinity
To 10 ml of a 7.5% w/v solution in carbon dioxide-free water add 0.05 ml of phenol red solution. Not more than 0.2 ml of either 0.01M hydrochloric acid VS or 0.01M sodium hydroxide VS is required to change the colour of the solution.
Arsenic
0.33 g dissolved in 25 ml of water complies with the limit test for arsenic, (3 ppm).
Heavy metals
Dissolve 1.3 g in 20 ml of water and add 1 g of ammonium chloride. 12 ml of the resulting solution complies with limit test A for heavy metals, Appendix VII. Use lead standard solution(1 ppm Pb) to prepare the standard (15 ppm).
Iron
0.33 g dissolved in 10 ml of water complies with the limit test for iron, Appendix VII (30 ppm).
Chloride
0.13 g dissolved in 15 ml of water complies with the limit test for chlorides, Appendix VII (400 ppm).
Insoluble matter
7.5 g dissolves in 20 ml of water, producing a solution which may be slightly turbid at first but which becomes clear in a few minutes.
Magnesium Sulphate HeptahydrateMagnesium Sulphate Heptahydrate BP Ph Eur Grade Specifications
Epsom Salts
MgSO4,7H2O -- 246.5 -- CAS 10034-99-8
Action and use
Osmotic laxative; used in treatment of electrolyte deficiency.DEFINITION
Content
99.0 per cent to 100.5 per cent (dried substance).CHARACTERS
Appearance
White or almost white, crystalline powder or brilliant, colourless crystals.
Solubility
Freely soluble in water, very soluble in boiling water, practically insoluble in ethanol (96 per cent).IDENTIFICATION
A. It gives the reactions of sulphates.
B. It gives the reaction of magnesium.TESTS
Solution S
Dissolve 5.0 g in water R and dilute to 50 ml with the same solvent.
Appearance of solution
Solution S is clear and colourless.
Acidity or alkalinity
To 10 ml of solution S add 0.05 ml of phenol red solution. Not more than 0.2 ml of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the colour of the indicator.
Chlorides
Maximum 300 ppm.
Arsenic
Maximum 2 ppm, determined on 0.5 g.
Iron
Maximum 20 ppm.
Heavy metals
Maximum 10 ppm.
Loss on drying
48.0 per cent to 52.0 per cent, determined on 0.500 g by drying in an oven at 110-120°C for 1 h and then at 400°C to constant mass.
Magnesium Sulfate USP Grade Specifications
MgSO4·xH2O
Sulfuric acid magnesium salt (1:1), hydrate.
Magnesium sulfate (1:1) monohydrate 138.36
Magnesium sulfate (1:1) heptahydrate 246.48 [CAS 10034-99-8].
Anhydrous 120.37 [CAS 7487-88-9].Magnesium Sulfate, rendered anhydrous by ignition, contains not less than 99.0 percent and not more than 100.5 percent of MgSO4.
Identification— A solution (1 in 20) resonds to the tests for Magnesium and for Sulfate.
pH: between 5.0 and 9.2, in a solution (1 in 20).
Loss on drying— Dry it at 105 for 2 hours: the anhydrous form loses not more than 2% of its weight.
Loss on ignition— Weigh accurately about 1 g in a crucible, heat at 105 for 2 hours, then ignite in a muffle furnace at 450 ± 25 to constant weight: the monohydrate loses between 13.0% and 16.0% of its weight, the dried form loses between 22.0% and 28.0% of its weight, and the heptahydrate loses between 40.0% and 52.0% of its weight.
Chloride— A 1.0-g portion shows no more chloride than corresponds to 0.20 mL of 0.020 N hydrochloric acid (0.014%).
Iron—
FOR MAGNESIUM SULFATE INTENDED FOR USE IN PREPARING NON-PARENTERAL DOSAGE FORMS—
Dissolve 0.50 g in 40 mL of water and proceed as directed in the test for Iron: the limit is 20 µg per g.
FOR MAGNESIUM SULFATE INTENDED FOR USE IN PREPARING PARENTERAL DOSAGE FORMS— the limit is 0.5 µg per g.
Heavy metals— Dissolve 2 g in 25 mL of water: the limit is 0.001%.
Selenium— The limit is 0.003%.
Magnesium Sulfate FCC Food Grade Specifications Magnesium Sulphate
Epsom Salt
MgSO4·xH2O Formula wt, monohydrate 138.38
Formula wt, heptahydrate 246.47
INS: 518
CAS: Magnesium Sulfate monohydrate 14168-73-1
CAS: Magnesium Sulfate heptahydrate 10034-99-8
CAS: Magnesium Sulfate dried 15244-36-7DESCRIPTION
Magnesium Sulfate occurs as a colorless crystal or a granular crystalline powder. It is produced with one or seven molecules of water of hydration or in a dried form containing the equivalent of about 2.3 waters of hydration. It is readily soluble in water, slowly soluble in glycerin, and sparingly soluble in alcohol.
Function: Nutrient.REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for Magnesium and for Sulfate.
Assay: Not less than 99.5% of MgSO4 after ignition.
Lead: Not more than 4 mg/kg.
Loss on Ignition Monohydrate: Between 13.0% and 16.0%; Heptahydrate: Between 40.0% and 52.0%; Dried: Between 22.0% and 28.0%.
Selenium: Not more than 0.003%.
Magnesium Sulfate Analytical Reagent Grade Specifications Magnesium Sulphate
Magnesium Sulfate Heptahydrate
MgSO4-7H2O
Formula Weight 246.48
CAS Number 10034-99-8REQUIREMENTS
Assay .............. 98.0-102.0% MgSO4-7H2O
pH of a 5% solution- 5.0-8.2 at 25CMAXIMUM ALLOWABLE
Insoluble matter ... 0.005%
Chloride (Cl) ...... 5 ppm
Nitrate (NO3) ...... 0.002%
Ammonium (NH4) ..... 0.002%
Calcium (Ca) ....... 0.02%
Manganese (Mn) ..... 5 ppm
Potassium (K) ...... 0.005%
Sodium (Na) ........ 0.005%
Strontium (Sr) ..... 0.005%
Heavy metals (as Pb) 5 ppm
Iron (Fe) .......... 5 ppm.Keywords: Magnesium Sulfate Sulphate Heptahydrate Monohydrtse Dried Anhydrous IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number anhydrous 7487-88-9 monohydrate 14168-73-1 dried 15244-36-7 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.
Manufacturers
ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIAe-mail: info@anmol.org
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