Fluorescein Sodium or Acid Yellow 73 BP Ph Eur USP Manufacturers

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Fluorescein Sodium or Acid Yellow 73 USP BP Ph Eur Grade Manufacturers

Anmol Chemicals is a manufacturer supplier exporter of Fluorescein Sodium or Acid Yellow 73 and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.

We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.

Synonyms: Fluorescein Sodium or Acid Yellow 73
CAS Number: 518-47-8, Molecular Weight: 376.27, Chemical Formula: C20H10Na2O5, EINECS EC Number: 208-253-0, FEMA: ----,

Fluorescein sodium or Acid Yellow 73, the sodium salt of fluorescein, is used extensively as a diagnostic tool in the field of ophthalmology and optometry. It is water-soluble form of fluorescein. Odorless and almost tasteless.

General Properties and Specifications of Fluorescein Sodium or Acid Yellow 73:
Appearance: Orange-red powder. Hygroscopic.
Odor: Odorless
Assay: >98%
Relative Density: about 1.6
Melting Point: >300C literature.
Boiling Point: 663C literature.
Flash Point: 217C literature.
Solubility: Soluble in water.
Storage: Room temperature. Preferably refrigerate.

Fluorescein Sodium BP Ph Eur Grade Specifications:
Soluble Fluorescein
C20H10Na2O5 --- 376.3 CAS 518-47-8
Action and use: Detection of corneal lesions, retinal angiography and pancreatic function testing.

CHARACTERS
Appearance: Orange-red, fine powder, hygroscopic.
Solubility: Freely soluble in water, soluble in ethanol (96 per cent), practically insoluble in hexane and in methylene chloride.

IDENTIFICATION
First identification: B, D
Second identification: A, C, D
A. Dilute 0.1 mL of solution S (see Tests) to 10 mL with water. The solution shows yellowish-green fluorescence. The fluorescence disappears on addition of 0.1 mL of dilute hydrochloric acid and reappears on addition of 0.2 mL of dilute sodium hydroxide solution.
B. Infrared absorption spectrophotometry.
C. The absorption by a piece of filter paper of 0.05 mL of the solution prepared for identification A (before the addition of dilute hydrochloric acid) colours the paper yellow. On exposing the moist paper to bromine vapour for 1 min and then to ammonia vapour, the colour becomes deep pink.
D. Ignite 0.1 g in a porcelain crucible. Dissolve the residue in 5 mL of water and filter. 2 mL of the filtrate gives reaction (a) of sodium.

TESTS
Solution S: Dissolve 1.0 g in carbon dioxide-free water prepared from distilled water and dilute to 50 mL with the same solvent.
Appearance of solution: Solution S is clear and orange-yellow with yellowish-green fluorescence.
pH:7.0 to 9.0 for solution S.
Related substances: To pass the test by liquid chromatography.
Chlorides: Maximum 0.25 per cent.
Sulfates: Maximum 1.0 per cent.
Zinc: Dilute 5 mL of solution S to 10 mL with water. Add 2 mL of hydrochloric acid, filter and add 0.1 mL of potassium ferrocyanide solution. No turbidity or precipitate is formed immediately.
Loss on drying: Maximum 10.0 per cent, determined on 1.000 g by drying in an oven at 105C.

Fluorescein Sodium USP Grade Specifications:
C20H10Na2O5 --- 376.27
Benzoic acid, 2-(6-hydroxy-3-oxo-3H -xanthene-9-yl), sodium salt (1:2);
Fluorescein disodium salt CAS 518-47-8
UNII: 93X55PE38X
UNII: TPY09G7XIR

DEFINITION
Fluorescein Sodium contains NLT 90.0% and NMT 102.0% of fluorescein sodium (C20H10Na2O5), calculated on the anhydrous basis.

IDENTIFICATION
A. A solution is strongly fluorescent, even in extreme dilution. The fluorescence disappears when the solution is made acid and reappears when the solution is again made alkaline.
B. Identification Tests—General, Sodium: The residue remaining after incineration meets the requirements.
C. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.

Zinc:
Sample solution: 10 mg/mL of Fluorescein Sodium in a saturated solution of sodium chloride.
Analysis: To 10 mL of Sample solution add 2 mL of 3 N hydrochloric acid. Shake well, filter, and add 1 mL of potassium ferrocyanide to the filtrate.
Acceptance criteria: No turbidity is produced.
Acriflavine:
Sample solution: 2 mg/mL of Fluorescein Sodium in water. Swirl the mixture, and filter.
Analysis: To the Sample solution add a few drops of 100-mg/mL sodium salicylate solution.
Acceptance criteria: No precipitate is formed.
Organic Impurities: To pass the test by chromatography.
Water Determination: NMT 17.0%
Packaging and Storage: Preserve in tight containers.

Keywords: Fluorescein Sodium or Acid Yellow 73 IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 518-47-8 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.

ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIA

Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.

Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.

All products are Sold for Industrial and Laboratory Use only. No other use is permitted.